(3-fluoro-5-methoxyphenyl)boronic acid - Names and Identifiers
(3-fluoro-5-methoxyphenyl)boronic acid - Physico-chemical Properties
Molecular Formula | C7H8BFO3
|
Molar Mass | 169.95 |
Density | 1.26±0.1 g/cm3(Predicted) |
Melting Point | 168-172 |
Boling Point | 305.5±52.0 °C(Predicted) |
Flash Point | 138.6°C |
Vapor Presure | 0.000357mmHg at 25°C |
pKa | 7.07±0.10(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.503 |
(3-fluoro-5-methoxyphenyl)boronic acid - Risk and Safety
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
R22 - Harmful if swallowed
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
HS Code | 29163990 |
Hazard Class | IRRITANT |
(3-fluoro-5-methoxyphenyl)boronic acid - Introduction
(3-fluoro-5-methoxyphenyl)boronic acid is an organic compound with the chemical formula C7H8BFNO3. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline powder
-Melting point: 115-118°C
-Solubility: Soluble in organic solvents such as chloroform, dimethyl sulfoxide and dichloromethane, slightly soluble in water.
Use:
-As an important intermediate in organic synthesis, it can be used to prepare compounds with pharmacological, pesticide or biological activity.
-It can be used to construct aryl borate groups in organic molecules, thereby developing new organic compounds.
Preparation Method:
(3-fluoro-5-methoxyphenyl) The preparation of boronic acid can be carried out by the following steps:
1. 3-fluoro-5-methoxyacetophenone reacts with boric acid under acidic conditions to generate an intermediate aryl borate.
2. After hydrolysis reaction, (3-fluoro-5-methoxyphenyl)boronic acid is obtained.
Safety Information:
-Follow laboratory safety procedures and wear personal protective equipment, such as protective glasses and gloves.
-Avoid contact with skin, eyes and inhalation of dust or gas. In case of accidental contact, rinse immediately with plenty of water.
-Avoid contact with oxidants, strong acids or strong alkalis during storage, and should be kept in a dry, well-ventilated place, and avoid direct sunlight.
Last Update:2024-04-10 22:29:15